Online mixture classification calculator

Serious damage to eyes / Eye irritation

Mixture's pH

According to 3.3.3.1.2 of Annex I to CLP "... a mixture is considered to cause serious eye damage (Category 1) if it has a pH ≤ 2 or a pH ≥ 11.5 ...". Therefore, if a mixture as a whole has such extreme pH it is classified as 'Eye Dam. 1'.

Non-additivity approach

The generic cut-off value for Serious eye damage/irritation is 1 % (CLP, Annex I, Table 1.1). This means that if mixture consists of substances classified as Serious eye damage or Serious eye irritation each present at a concentration below 1 % and even if the sum of their concentrations is above 1 % the mixture will not be classified for Serious eye damage/irritation.

Other hand, in case of acids, bases, inorganic salts, aldehydes, phenols and surfactants such approach is not applicable, because many such substances are seriously damaging to the eye/eye irritant at concentrations < 1 %. A mixture containing such ingredients cannot be classified on the basis of the additivity approach. In this case Serious eye damage/irritation is calculated based on approach described in Annex I, 3.3.3.3.4.3 and Table 3.3.4 to CLP.

In the table below generic concentration limits of ingredients that trigger classification of the mixture as Serious eye damage/irritation are presented.

Ingredient	Concentration in mixture	Mixture classified as
Acid with pH ≤ 2	≥ 1 %	Eye Dam. 1
Base with pH ≥ 11.5	≥ 1 %	Eye Dam. 1
Other ingredient classified as skin corrosion (sub-category 1A, 1B, 1C or Category 1) or serious eye damage (Category 1)	≥ 1 %	Eye Dam. 1
Other ingredient classified as eye irritation (Category 2)	≥ 3 %	Eye Irrit. 2

Additivity approach

The table below represents generic concentration limits of ingredients classified as Skin corrosion (Category 1, 1A, 1B or 1C) and/or Serious eye damage (Category 1) or Eye irritation (Category 2) that trigger classification of the mixture as Serious eye damage or Eye irritation where the additivity approach applies (CLP, Annex I, Table 3.3.3):

Sum of ingredients classified as

Concentration triggering classification of a mixture as

Sum of ingredients classified as	Eye Dam. 1	Eye Irrit. 2
Skin Corr. 1A + Skin Corr. 1B + Skin Corr. 1C + Skin Corr. 1 + Eye Dam. 1 (see note)	≥ 3 %	≥ 1 % but < 3 %
Eye Irrit. 2		≥ 10 %
10 × (Skin Corr. 1A + Skin Corr. 1B + Skin Corr. 1C + Skin Corr. 1 + Eye Dam. 1) + Eye Irrit. 2		≥ 10 %

Note.

If an ingredient is classified as both:

−	Skin Corrosion sub-category 1A or 1B or 1C or Category 1 and
−	Serious Eye Damage Category 1

its concentration is considered only once in the calculation.

The below approach should be used to calculate Serious eye damage:

●	To classify mixture as Eye Dam. 1 concentration of ingredients with - 'Skin Corr. 1' and - 'Skin Corr. 1A' and - 'Skin Corr. 1B' and - 'Skin Corr. 1C' and - 'Eye Dam. 1' are added. If their sum is ≥ 3 % the mixture is classified as 'Eye Dam. 1'.

The below approach should be used to calculate Eye irritation:

●

If the sum of all ingredients with 'Eye Irrit. 2' is ≥ 10 % the mixture is classified as Eye Irrit. 2 .

●

If mixture contains ingredients classified as Skin corrosion (sub-)categories 1A, 1B, 1C or 1 and Serious eye damage category 1 their concentration values must be summed and multiplied by 10. Additionally, if mixture contains ingredients with Eye irritation category 2 their concentration values (without multiplication) should be added. If final sum value is ≥ 10 % the mixture is classified as Eye Irrit. 2 .

For calculation the serious eye damage/eye irritation properties of the mixtures, only 'relevant ingredients' are taken into account.

The 'relevant ingredients' of a mixture are those which are present in concentrations ≥ 1 % (w/w for solids, liquids, dusts, mists and vapours and v/v for gases), unless there is a presumption (e.g. in the case of skin corrosive ingredients) that an ingredient present at a concentration < 1 % can still be relevant for classifying the mixture for serious eye damage/eye irritation (CLP, Annex I, 3.3.3.3.1).

●	If mixture contains an ingredient classified as 'Eye Dam. 1' or 'Eye Irrit. 2' at concentration below 1 % such ingredient is not taken into account because: − its concentration is below cut-off limit 1 %(CLP, Annex I, table 1.1), − it is not a 'relevant ingredient'.
●	If mixture contains an ingredient classified as 'Skin Corr. 1A' or 'Skin Corr. 1B' or 'Skin Corr. 1C' or 'Skin Corr. 1' at concentration < 1 % such ingredient is not taken into account because: − it is not a 'relevant ingredient'.

Hierarchy of hazard categories

Hazard

➔

−	Serious eye damage, category 1 (Eye Dam. 1: H318)
−	Eye irritation, category 2 (Eye Irrit. 2: H319)

A more severe classification for a mixture overrides a less severe classification. For example, if ingredients of a mixture lead to classification both as serious eye damage category 1 (Eye Dam. 1) and eye irritation category 2 (Eye Irrit. 2) the category ''Eye Dam. 1' must be selected.

In accordance to Article 27 and Part 1 of Annex III to CLP, if the hazard statement H314 'Causes severe skin burns and eye damage' is assigned, the hazard statement H318 'Causes serious eye damage' does not need to be indicated in hazard communication (label, section 2.2 of safety data sheet). Taking into account the above and Guidance on the Application of the CLP Criteria, Part 3: Health Hazards, Version 5.0, Nov 2024, section 3.3.2.4, if a mixture is classified both as:

−	Skin Corr. 1 or 1A or 1B or 1C (H314 - Causes severe skin burns and eye damage)
	and
−	Eye Dam. 1 (H318 - Causes serious eye damage)

the statement H318 may be omitted because of redundancy.

To select pictogram, signal word, hazard and precautionary statements please refer to Annex I, part 3, Table 3.3.5 of Regulation (EC) no 1272/2008 (CLP).

Example 1

Example 2

Example 3

Example 4

Example 5

Example 6

Example 7

Example 8

There is a mixture:

Ingredient	Conc. % (w/w)	Classification
Substance P	1.5	Skin Corr. 1A: H314
Substance R	2.5	Skin Corr. 1C: H314
Substance S	2.0	Eye Dam. 1: H318
Water	94.0	−

Cut-off limits

−	Concentration of substance S is above the generic cut-off limit 1 % (CLP, Annex I, Table 1.1), therefore, its concentration is taken into account.

Relevant ingredients

−	Substances P and R have influence on classification of serious eye damage / eye irritation. Their concentrations are above 1 % (CLP, Annex I, 3.2.3.3.1), therefore, P and R are 'relevant ingredients' and are taken into account.

Specific and Generic concentration limits

−	Because no specific concentration limits are applied for any ingredient, concentrations of mixture's ingredients must be compared to generic concentration limits.

Additivity vs. Non-additivity approach

−	The mixture's pH is between 2 and 11.5, therefore, additivity approach is applied for calculation of serious damage to eyes / eye irritation hazard.

Calculation of 'Eye Dam. 1'

−	Concentrations of substances P, R and S must be summed. conc. P + conc. R + conc. S = 1.5 + 2.5 + 2.0 = 6.0 % The obtained value is above the generic concentration limit 3 %. This leads to classification Eye Dam. 1 .

Calculation of 'Eye Irrit. 2'

−

Mixture does not contain ingredient with 'Eye Irrit. 2'. Concentrations of substances P, R and S must be summed and multiplied by 10.

10 × (conc. P + conc. R + conc. S) = 10 × (1.5 + 2.5 + 2.0) = 60 %

The obtained value is above the generic concentration limit 10 %. This leads to classification Eye Irrit. 2 .

Substances P and R lead also to classification Skin Irrit. 2 , because the sum of their concentrations is between 1 % and 5 % (see CLP, Annex I, Table 3.2.3). As a consequence following have to be taken into account: hazard statement H315, pictogram GHS07, signal word 'Warning' and precautionary statements P264, P280, P302+P352, P321, P332+P313, P362+P364.

Selection of hazard category

−	Classification category 'Eye Dam. 1' is more severe than 'Eye Irrit. 2', therefore, mixture is classified as 'Eye Dam. 1'.
−	Classification category 'Skin Irrit. 2' is also applied.

Selection of hazard statements

−	H318 corresponds to 'Eye Dam. 1'.
−	H315 corresponds to 'Skin Irrit. 2'.

Selection of pictogram and signal word

−	Pictogram GHS05 and signal word 'Danger' correspond to 'Eye Dam. 1'.
−	Pictogram GHS07 and signal word 'Warning' correspond to 'Skin Irrit. 2'.
−	According to Article 26(1,c) to CLP if the hazard pictogram GHS05 applies, the GHS07 is not used if it results from 'Skin Irrit. 2' and/or 'Eye Irrit. 2'.
−	According to Article 20(3) to CLP if the signal word 'Danger' is used, the 'Warning' is not used.

Selection of precautionary statements

−	For H318 following precautionary statements are applied: P280, P305+P351+P338, P310.
−	For H315 following precautionary statements are applied: P264, P280, P302+P352, P321, P332+P313, P362+P364.

Classification and labelling of the mixture

Classification:	Skin Irrit. 2, Eye Dam. 1
Hazard statements:	H315, H318
Pictogram:
	GHS05
Signal word:	Danger
Precautionary statements:	P264, P280, P302+P352, P305+P351+P338, P310, P321, P332+P313, P362+P364

If mixture has more than 6 precautionary statements, the most important should be indicated on the label and in section 2 of SDS, unless necessary to reflect the nature and the severity of the hazards (CLP, Article 28(3)). The rest may be placed in section 16 'Other information' of SDS.

There is a mixture:

Ingredient	Conc. % (w/w)	Classification
Substance P	1.5	Skin Corr. 1A: H314
Substance R	0.5	Skin Corr. 1C: H314
Substance S	2.0	Eye Dam. 1: H318
Substance T	0.9	Eye Dam. 1: H318
Water	95.1	−

Cut-off limits

−	Concentration of substance S is above the generic cut-off limit 1 % (CLP, Annex I, Table 1.1), therefore, its concentration is taken into account.
−	Concentration of substance T is below the generic cut-off limit 1 % (CLP, Annex I, Table 1.1), therefore, its concentration is not taken into account.

Relevant ingredients

Substances P and R have influence on classification of serious eye damage / eye irritation.

−	Concentration of substance P is above 1 % (CLP, Annex I, 3.2.3.3.1), therefore, P is a 'relevant ingredient' and is taken into account.
−	Concentration of substance R is below 1 % (CLP, Annex I, 3.2.3.3.1), therefore, R is not a 'relevant ingredient' and is not taken into account.

Specific and Generic concentration limits

−	Because no specific concentration limits are applied for any ingredient, concentrations of mixture's ingredients must be compared to generic concentration limits.

Additivity vs. Non-additivity approach

−	The mixture's pH is between 2 and 11.5, therefore, additivity approach is applied for calculation of serious damage to eyes / eye irritation hazard.

Calculation of 'Eye Dam. 1'

−	Concentrations of substances P and S must be summed. conc. P + conc. S = 1.5 + 2.0 = 3.5 % The obtained value is above the generic concentration limit 3 %. This leads to classification Eye Dam. 1 .

Calculation of 'Eye Irrit. 2'

−	Mixture does not contain ingredient with 'Eye Irrit. 2'. Concentrations of substances P and S must be summed and multiplied by 10. 10 × (conc. P + conc. S) = 10 × (1.5 + 2.0) = 35 % The obtained value is above the generic concentration limit 10 %. This leads to classification Eye Irrit. 2 .

Substance P leads also to classification Skin Irrit. 2 , because its concentration is between 1 % and 5 % (see CLP, Annex I, Table 3.2.3). As a consequence following have to be taken into account: hazard statement H315, pictogram GHS07, signal word 'Warning' and precautionary statements P264, P280, P302+P352, P321, P332+P313, P362+P364.

Selection of hazard category

−	Classification category 'Eye Dam. 1' is more severe than 'Eye Irrit. 2', therefore, mixture is classified as 'Eye Dam. 1'.
−	Classification category 'Skin Irrit. 2' is also applied.

Selection of hazard statements

−	H318 corresponds to 'Eye Dam. 1'.
−	H315 corresponds to 'Skin Irrit. 2'.

Selection of pictogram and signal word

−	Pictogram GHS05 and signal word 'Danger' correspond to 'Eye Dam. 1'.
−	Pictogram GHS07 and signal word 'Warning' correspond to 'Skin Irrit. 2'.
−	According to Article 26(1,c) to CLP if the hazard pictogram GHS05 applies, the GHS07 is not used if it results from 'Skin Irrit. 2' and/or 'Eye Irrit. 2'.
−	According to Article 20(3) to CLP if the signal word 'Danger' is used, the 'Warning' is not used.

Selection of precautionary statements

−	For H318 following precautionary statements are applied: P280, P305+P351+P338, P310.
−	For H315 following precautionary statements are applied: P264, P280, P302+P352, P321, P332+P313, P362+P364.

Classification and labelling of the mixture

Classification:	Skin Irrit. 2, Eye Dam. 1
Hazard statements:	H315, H318
Pictogram:
	GHS05
Signal word:	Danger
Precautionary statements:	P264, P280, P302+P352, P305+P351+P338, P310, P321, P332+P313, P362+P364

Ingredient	Conc. % (w/w)	Classification
Substance D	0.9	Eye Irrit. 2: H319
Substance E	5.5	Eye Irrit. 2: H319
Substance G	4.0	Eye Irrit. 2: H319
Water	89.6	−

There is a mixture:

Ingredient	Conc. % (w/w)	Classification
Substance P	1.2	Skin Corr. 1A: H314
Substance S	1.4	Eye Dam. 1: H318
Substance E	5.5	Eye Irrit. 2: H319
Substance G	4.0	Eye Irrit. 2: H319
Water	87.9	−

Cut-off limits

−	Concentrations of substances S, E and G are above the generic cut-off limit 1 % (CLP, Annex I, Table 1.1), therefore, their concentrations are taken into account.

Relevant ingredients

−	Substance P has influence on classification of serious eye damage / eye irritation. Its concentration is above of 1 % (CLP, Annex I, 3.2.3.3.1), therefore, P is a 'relevant ingredient' and is taken into account.

Specific and Generic concentration limits

−	Because no specific concentration limits are applied for any ingredient, concentrations of mixture's ingredients must be compared to generic concentration limits.

Additivity vs. Non-additivity approach

−	The mixture's pH is between 2 and 11.5, therefore, additivity approach is applied for calculation of serious damage to eyes / eye irritation hazard.

Calculation of 'Eye Dam. 1'

−	Concentrations of substances P and S must be summed. conc. P + conc. S = 1.2 + 1.4 = 2.6 % The obtained value is below the generic concentration limit 3 %. This does not lead to classification 'Eye Dam. 1'.

Calculation of 'Eye Irrit. 2'

−	Concentrations of substances P and S must be summed. conc. P + conc. S = 1.2 + 1.4 = 2.6 % The obtained value is between 1 % and 3 % of the generic concentration limits. This leads to classification Eye Irrit. 2 .

−	Concentrations of substances P and S must be summed and multiplied by 10. To this value concentrations of substances E and G must be added (without multiplication). 10 × (conc. P + conc. S) + conc. E + conc. G = 10 × (1.2 + 1.4) + 5.5 + 4.0 = 35.5 % The obtained value is above the generic concentration limit 10 %. This leads to classification Eye Irrit. 2.

−	Concentrations of substances E and G must be summed. conc. E + conc. G = 5.5 + 4.0 = 9.5 % The obtained value is below the generic concentration limit 10 %. This does not lead to classification 'Eye Irrit. 2'.

Selection of hazard category

−	The mixture is classified as 'Eye Irrit. 2'.
−	Classification category 'Skin Irrit. 2' is also applied.

Selection of hazard statements

−	H319 corresponds to 'Eye Irrit. 2'.
−	H315 corresponds to 'Skin Irrit. 2'.

Selection of pictogram and signal word

−	Pictogram GHS07 and signal word 'Warning' correspond to both 'Eye Irrit. 2' and 'Skin Irrit. 2'.

Selection of precautionary statements

−	For H319 following precautionary statements are applied: P264, P280, P305+P351+P338, P337+P313.
−	For H315 following precautionary statements are applied: P264, P280, P302+P352, P321, P332+P313, P362+P364.

Classification and labelling of the mixture

Classification:	Skin Irrit. 2, Eye Irrit. 2
Hazard statements:	H315, H319
Pictogram:
	GHS07
Signal word:	Warning
Precautionary statements:	P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, P362+P364

There is a mixture:

Ingredient	Conc. % (w/w)	Classification
Substance P	3.0	Skin Corr. 1A: H314
Substance R	2.5	Skin Corr. 1C: H314
Substance G	4.0	Eye Irrit. 2: H319
Water	90.5	−

Cut-off limits

−	Concentration of substance G is above the generic cut-off limit 1 % (CLP, Annex I, Table 1.1), therefore, its concentration is taken into account.

Relevant ingredients

−	Substances P and R have influence on classification of serious eye damage / eye irritation. Their concentrations are above 1 % (CLP, Annex I, 3.2.3.3.1), therefore, P and R are 'relevant ingredients' and are taken into account.

Specific and Generic concentration limits

−	Because no specific concentration limits are applied for any ingredient, concentrations of mixture's ingredients must be compared to generic concentration limits.

Additivity vs. Non-additivity approach

−	The mixture's pH is between 2 and 11.5, therefore, additivity approach is applied for calculation of serious damage to eyes / eye irritation hazard.

Calculation of 'Eye Dam. 1'

−	Concentrations of substances P and R must be summed. conc. P + conc. R = 3.0 + 2.5 = 5.5 % The obtained value is above the generic concentration limit 3 %. This leads to classification Eye Dam. 1 .

Calculation of 'Eye Irrit. 2'

−

Concentrations of substances P and R must be summed and multiplied by 10. To this value concentration of substance G must be added (without multiplication).

10 × (conc. P + conc. R) + conc. G = 10 × (3.0 + 2.5) + 4.0 = 54.0 %

The obtained value is above the generic concentration limit 10 %. This leads to classification Eye Irrit. 2 .

Substances P and R lead also to classification Skin Corr. 1C , because the sum of their concentrations is ≥ 5 % (see CLP, Annex I, Table 3.2.3). As a consequence following have to be taken into account: hazard statement H314, pictogram GHS05, signal word 'Danger' and precautionary statements P301+P330+P331, P303+P361+P353, P363, P304+P340, P310, P321, P305+P351+P338, P405, P501.

Selection of hazard category

−	Classification category 'Eye Dam. 1' is more severe than 'Eye Irrit. 2', therefore, mixture is classified as 'Eye Dam. 1'.
−	Classification category 'Skin Corr. 1C' is also applied.

Selection of hazard statements

−	H314 corresponds to 'Skin Corr. 1C'.
−	H318 corresponds to 'Eye Dam. 1', but accorging to Part 1 of Annex III to CLP if H314 is assigned then H318 does not need to be indicated.

Selection of pictogram and signal word

−	Pictogram GHS05 and signal word 'Danger' correspond to both 'Skin Corr. 1C' and 'Eye Dam. 1'.

Selection of precautionary statements

−	For H314 following precautionary statements are applied: P260, P264, P280, P301+P330+P331, P303+P361+P353, P363, P304+P340, P310, P321, P305+P351+P338, P405, P501.

Classification and labelling of the mixture

Classification:	Skin Corr. 1C, Eye Dam. 1
Hazard statements:	H314
Pictogram:
	GHS05
Signal word:	Danger
Precautionary statements:	P260, P264, P280, P301+P330+P331, P303+P361+P353, P363, P304+P340, P310, P321, P305+P351+P338, P405, P501

There is a mixture:

Ingredient	Conc. % (w/w)	Classification	Specific Conc. Limits (SCLs)
Substance A	1.2	Eye Dam. 1: H318	−
Substance B	1.3	Eye Dam. 1: H318	−
Substance C	2.0	Eye Dam. 1: H318	Eye Dam. 1: H318: C ≥ 22 % Eye Irrit. 2: H319: 14 % ≤ C < 22 %
Water	95.5	−	−

Cut-off limits

−	Concentrations of substances A, B and C are above the generic cut-off limit 1 % (CLP, Annex I, Table 1.1), therefore, their concentrations are taken into account.

Specific and Generic concentration limits

−	Because no specific concentration limits are applied for substances A and B, their concentrations must be compared to generic concentration limits.
−	Substance C has specific concentration limits (SCLs). Because SCL has a precedence over generic concentration limit, concentration of C must be compared to its SCLs.

Additivity vs. Non-additivity approach

−	The mixture's pH is between 2 and 11.5, therefore, additivity approach is applied for calculation of serious damage to eyes / eye irritation hazard.

Calculation of 'Eye Dam. 1'

−

Concentration of substance C is below its SCL 22 %. This does not lead to classification 'Eye Dam. 1'.

−

Because substance C has SCL for 'Eye Dam. 1', the formula from Guidance on the Application of the CLP Criteria, Part 1: General Principles for Classification and Labelling, Version 5.0, Nov 2024, section 1.6.3.3.3 is applied.

^conc. A / _GCL + ^conc. B / _GCL + ^conc. C / _SCL = ^1.2 / ₃ + ^1.3 / ₃ + ^2.0 / ₂₂ = 0.924

GCL for 'Eye Dam. 1' is 3 % (CLP, Annex I, Table 3.3.3).

The obtained value is below 1. This does not lead to classification 'Eye Dam. 1'.

Calculation of 'Eye Irrit. 2'

−

Concentration of substance C is below its SCL 14 % (lower border for 'Eye Irrit. 2'). This does not lead to classification 'Eye Irrit. 2'.

−

Because substance C has SCL for 'Eye Irrit. 2', the formula from Guidance on the Application of the CLP Criteria, Version 5.0 July 2017, section 1.6.3.3.3 is applied.

^conc. A / _GCL + ^conc. B / _GCL + ^conc. C / _SCL = ^1.2 / ₁ + ^1.3 / ₁ + ^2.0 / ₁₄ = 2.643

For 'Eye Irrit. 2' two GCLs are applied (CLP, Annex I, Table 3.3.3):

- 1 % (as lower border of 1 % ≤ C < 3 %) if calculation is based on 'Skin Corr. 1A', 'Skin Corr. 1B', 'Skin Corr. 1C', 'Skin Corr. 1' and 'Eye Dam. 1',

- 10 % if calculation is based on 'Eye Irrit. 2'.

Because substances A and B are classified as 'Eye Dam. 1' the GCL equals to 1. Because substance C has SCL equals to 14 % corresponding to 'Eye Irrit. 2', this value is used in formula.

The obtained value is above 1. This leads to classification Eye Irrit. 2 .

Selection of hazard category

−	The mixture is classified as 'Eye Irrit. 2'.

Selection of hazard statements

−	H319 corresponds to 'Eye Irrit. 2'.

Selection of pictogram and signal word

−	Pictogram GHS07 and signal word 'Warning' correspond to 'Eye Irrit. 2'.

Selection of precautionary statements

−	For H319 following precautionary statements are applied: P264, P280, P305+P351+P338, P337+P313.

Classification and labelling of the mixture

Classification:	Eye Irrit. 2
Hazard statements:	H319
Pictogram:
	GHS07
Signal word:	Warning
Precautionary statements:	P264, P280, P305+P351+P338, P337+P313

There is a mixture:

Ingredient	Conc. % (w/w)	Classification	Specific Conc. Limits (SCLs)
Substance C	7.0	Eye Dam. 1: H318	Eye Dam. 1: H318: C ≥ 22 % Eye Irrit. 2: H319: 14 % ≤ C < 22 %
Substance E	4.5	Eye Irrit. 2: H319	−
Water	88.5	−	−

Cut-off limits

−	Concentrations of substances C and E are above the generic cut-off limit 1 % (CLP, Annex I, Table 1.1), therefore, their concentrations are taken into account.

Specific and Generic concentration limits

−	Substance C has specific concentration limits (SCLs). Because SCL has a precedence over generic concentration limit, concentration of C must be compared to its SCLs.
−	Because no specific concentration limits are applied for substance E, its concentration must be compared to generic concentration limit.

Additivity vs. Non-additivity approach

−	The mixture's pH is between 2 and 11.5, therefore, additivity approach is applied for calculation of serious damage to eyes / eye irritation hazard.

Calculation of 'Eye Dam. 1'

−	Concentration of substance C is below its SCL 22 %. This does not lead to classification 'Eye Dam. 1'.

Calculation of 'Eye Irrit. 2'

−

Concentration of substance C is below its SCL 14 % (lower border for 'Eye Irrit. 2'). This does not lead to classification 'Eye Irrit. 2'.

−

Because substance C has SCL for 'Eye Irrit. 2', the formula from Guidance on the Application of the CLP Criteria, Part 1: General Principles for Classification and Labelling, Version 5.0, Nov 2024, section 1.6.3.3.3 is applied.

^conc. C / _SCL + ^conc. E / _GCL = ^7.0 / ₁₄ + ^4.5 / ₁₀ = 0.950

For 'Eye Irrit. 2' two GCLs are applied (CLP, Annex I, Table 3.3.3):

- 1 % (as lower border of 1 % ≤ C < 3 %) if calculation is based on 'Skin Corr. 1A', 'Skin Corr. 1B', 'Skin Corr. 1C', 'Skin Corr. 1' and 'Eye Dam. 1',

- 10 % if calculation is based on 'Eye Irrit. 2'.

Because substance C has SCL equals to 14 % corresponding to 'Eye Irrit. 2', this value is used in formula. Because substance E is classified as 'Eye Irrit. 2' the GCL equals to 10.

The obtained value is below 1. This does not lead to classification 'Eye Irrit. 2'.

Classification of the mixture

Mixture is not classified.

There is a mixture:

Ingredient	Conc. % (w/w)	Classification	Specific Conc. Limits (SCLs)
Substance A	0.9	Eye Dam. 1: H318	−
Substance C	2.7	Eye Dam. 1: H318	Eye Dam. 1: H318: C ≥ 22 % Eye Irrit. 2: H319: 14 % ≤ C < 22 %
Substance E	9.5	Eye Irrit. 2: H319	−
Substance G	4.0	Skin Corr. 1A: H314	Skin Corr. 1A: H314: C ≥ 20 % Skin Corr. 1B: H314: 5 % ≤ C < 20 %
Water	82.9	−	−

In this example, the calculation of only serious eye damage / eye irritation classification is described.

Cut-off limits

−	Concentration of substance A is below the generic cut-off limit 1 % (CLP, Annex I, Table 1.1), therefore, its concentration is not taken into account.
−	Concentrations of substances C and E are above the generic cut-off limit 1 % (CLP, Annex I, Table 1.1), therefore, their concentrations are taken into account.

Relevant ingredients

−	Substance G has influence on classification of serious eye damage / eye irritation. Its concentration is above of 1 % (CLP, Annex I, 3.2.3.3.1), therefore, G is a 'relevant ingredient' and is taken into account.

Specific and Generic concentration limits

−	Because no specific concentration limits are applied for substance E, its concentration must be compared to generic concentration limit.
−	Substances C and G have specific concentration limits (SCLs). Because SCL has a precedence over generic concentration limit, concentrations of C and G must be compared to their SCLs.

Additivity vs. Non-additivity approach

−	The mixture's pH is between 2 and 11.5, therefore, additivity approach is applied for calculation of serious damage to eyes / eye irritation hazard.

Calculation of 'Eye Dam. 1'

−

Concentration of substance C is below its SCL 22 %. This does not lead to classification 'Eye Dam. 1'.

−

Mixture contains 2 substances (C and G) which have influence on 'Eye Dam. 1'. Both of them have SCL, therefore, the formula from Guidance on the Application of the CLP Criteria, Part 1: General Principles for Classification and Labelling, Version 5.0, Nov 2024, section 1.6.3.3.3 is applied.

^conc. C / _SCL + ^conc. G / _SCL = ^2.7 / ₂₂ + ^4.0 / ₅ = 0.923

- For substance C the SCL 22 % is applied as for 'Eye Dam. 1',

- Because classifications 'Skin Corr. 1A', 'Skin Corr. 1B', 'Skin Corr. 1C', 'Skin Corr. 1' have influence on 'Eye Dam. 1' for substance G the lower border 5 % of its SCL for 'Skin Corr. 1B' is applied.

The obtained value is below 1. This does not lead to classification 'Eye Dam. 1'.

Calculation of 'Eye Irrit. 2'

−

Concentration of substance C is below its SCL 14 % (lower border for 'Eye Irrit. 2'). This does not lead to classification 'Eye Irrit. 2'.

−

^conc. C / _SCL + ^conc. E / _GCL = ^2.7 / ₁₄ + ^9.5 / ₁₀ = 1.143

For 'Eye Irrit. 2' two GCLs are applied (CLP, Annex I, Table 3.3.3):

- 1 % (as lower border of 1 % ≤ C < 3 %) if calculation is based on 'Skin Corr. 1A', 'Skin Corr. 1B', 'Skin Corr. 1C', 'Skin Corr. 1' and 'Eye Dam. 1',

- 10 % if calculation is based on 'Eye Irrit. 2'.

Because substance C has SCL equals to 14 % corresponding to 'Eye Irrit. 2', this value is used in formula. Because substance E is classified as 'Eye Irrit. 2' the GCL equals to 10.

The obtained value is above 1. This leads to classification Eye Irrit. 2 .

The mixture is also classified as Skin Irrit. 2. As a consequence following have to be taken into account: hazard statement H315, pictogram GHS07, signal word 'Warning' and precautionary statements P264, P280, P302+P352, P321, P332+P313, P362+P364.

Selection of hazard category

−	The mixture is classified as 'Eye Irrit. 2'.
−	Classification category 'Skin Irrit. 2' is also applied.

Selection of hazard statements

−	H319 corresponds to 'Eye Irrit. 2'.
−	H315 corresponds to 'Skin Irrit. 2'.

Selection of pictogram and signal word

−	Pictogram GHS07 and signal word 'Warning' correspond to both 'Eye Irrit. 2' and 'Skin Irrit. 2'.

Selection of precautionary statements

−	For H319 following precautionary statements are applied: P264, P280, P305+P351+P338, P337+P313.
−	For H315 following precautionary statements are applied: P264, P280, P302+P352, P321, P332+P313, P362+P364.

Classification and labelling of the mixture

Classification:	Eye Irrit. 2, Skin Irrit. 2
Hazard statements:	H319, H315
Pictogram:
	GHS07
Signal word:	Warning
Precautionary statements:	P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P362+P364, P337+P313

−	Concentrations of substances E and G are above the generic cut-off limit 1 % (CLP, Annex I, Table 1.1), therefore, their concentrations are taken into account.
−	Concentration of substance D is below the generic cut-off limit 1 % (CLP, Annex I, Table 1.1), therefore, its concentration is not taken into account.