For some hazard classes additivity concept is applied, but for some is not.
If a mixture contains two or more substances each is classified of the same category for which additivity is applied, the summation of their concentrations must be done to check if mixture is classified in this category. If the sum equals or exceeds the Generic Concentration Limit (GCL) set out for this hazard class/category, the mixture must be classified for that hazard. For substances that have an SCL or M-factor(s), these are taken into account.
In turn, if a mixture contains substances classified of the same category, but additivity is not applied and each substance present at a concentration below the Generic Concentration Limit (GCL) defined for that hazard class/category, such a mixture will not be classified even if the sum of the substances' concentrations is above GCL (as far as no lower SCL has been set).
● | Acute (oral/dermal/inhalation) toxicity. |
● | Skin corrosion/irritation (besides the cases mentioned in 3.2.3.3.4 of Annex I to CLP). |
● | Serious eye damage/eye irritation (besides the cases mentioned in 3.3.3.3.4 of Annex I to CLP). |
● | Specific target organ toxicity, single exposure Category 3 (respiratory tract irritation). |
● | Specific target organ toxicity, single exposure Category 3 (narcotic effects). |
● | Aspiration hazard (plus consideration of viscosity of the final mixture). |
● | Hazardous to the aquatic environment, short-term (acute) and long-term (chronic). |
● | Respiratory and Skin sensitisation. |
● | Germ cell mutagenicity. |
● | Carcinogenicity. |
● | Reproductive toxicity. |
● | Specific target organ toxicity, single exposure, categories 1 and 2. |
● | Specific target organ toxicity, repeated exposure, categories 1 and 2. |
● | Endocrine disruption for human health, categories 1 and 2. |
● | Endocrine disruption for the environment, categories 1 and 2. |
● | Persistent, Bioaccumulative and Toxic or very Persistent, very Bioaccumulative. |
● | Persistent, Mobile and Toxic or very Persistent, very Mobile. |
● | Hazardous for the ozone layer. |